You're going to look like a tourist most places you go, so why not go in style with Cotopaxi's Cusco 26L Backpack. Available in four colors, the Cusco is currently 33% off here.

Featuring an internal laptop sleeve that fits up to a 15-in laptop, the Cusco is a perfect option to carry all your gear on a short trip, or act as a daybag on longer excursions. 

I'm partial to the Beech Canopy color (seen here) for it's understated look and suede leather accessories. Rugged and water resistant, the Cusco also has two side slots for water bottles. 

Looking for something a bit smaller, Cotopaxi's Kilimanjaro 20L is also on sale for 37% off.